Radiotherapy in the management of leukemia.

Localized radiation therapy directed to the spleen and other sites, supplemented by a whole-body radiation technique, appeared to increase survival time in the chronic leukemias. In recent years the alkylating drugs have provided a more convenient form of "whole-body effect", because treatment can be taken at home and yet observation maintained.Small or medium field radiation therapy remains the most efficient means of controlling localized leukemic infiltrations. Splenic irradiation has been used successfully in the control of hemolytic anemia occurring during the course of chronic leukemia where steroids have failed.Proper management of the leukemias requires close co-operation between the radiotherapist, internist and hematologist.